19 of Medvedev's twenty-one titles have been earned on hard surfaces
A comeback the Russian player secured his first championship for 882 days with a win over Corentin Moutet in the competition championship match.
The athlete, a former number one, has had a challenging year, winning just one win at the Grand Slams and experiencing a meltdown at the New York tournament.
Medvedev's unpredictability on the ATP Tour - and difficulties with his service game in particular - led to him exiting of the top ten and eventually separating with long-time coach Cervara.
Currently training with Thomas Johansson and Rohan Goetzke, Medvedev has steadily progressed in the recent weeks - culminating in a tightly fought competitive victory over challenger Moutet.
This represents the player's first trophy following the Rome competition and maiden on a hard surface since that period of that year.
Success also signifies he has achieved 21 titles at twenty-one distinct tournaments.
"For the first time I have attended a event with my children simultaneously, so to get a championship is especially meaningful," commented ranked player Medvedev.
"This championship is in dedication of my second daughter my daughter, because the initial championship I achieved when my older daughter her name was born was for her."
Medvedev, the former major winner, had been defeated in his last six title deciders, comprising in the German tournament in the past months.
His defensive approach and frequent reactions on court had led observers to wonder if his ability to perform at the top level was finished.
However the 29-year-old has made changes in the past month, attempting to advance forward and compete assertively, reinforced by an enhanced serve.
He recovered from a break down in the first set against the challenging Frenchman, securing four of the last five points to gain the advantage.
Both players traded service breaks in the second set before Moutet, bidding for his first ATP Tour victory, took control to push for a decider.
Moutet saved 4 early break points in a close final set before the champion secured a break to that score to serve for the match.
Fittingly, the winner earned the title with a shot at the front of the court, with the Frenchman unable to control a return after over two and a half hours.